CJC-1295
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Research summary
CJC-1295 is a synthetic analog of growth hormone-releasing hormone (GHRH) engineered to bind circulating albumin after injection, extending its half-life well beyond natural GHRH so it can continuously stimulate the pituitary to release growth hormone.
In a randomized study in healthy adult volunteers, a single CJC-1295 injection produced dose-dependent 2- to 10-fold increases in plasma growth hormone lasting six or more days, and 1.5- to 3-fold increases in IGF-1 lasting 9-11 days. A separate human study found GH was released with preserved natural pulsatility rather than flattened secretion. In GHRH-knockout mice, daily low-dose injections normalized growth, while less frequent dosing produced only partial effects.
Sources: Journal of Clinical Endocrinology & Metabolism, 2006 (Teichman et al.); American Journal of Physiology, 2006 (Alba et al.). Findings from published research —not a claim about this product, and not evidence of safety or effectiveness for human use.
Decoding the Benefits
- A single dose pushed growth hormone output up to 10-fold above baseline, with elevated levels persisting nearly a week.
- IGF-1 stayed elevated even longer — over a week and a half — after just one injection.
- Preserved the body's natural pulsed release pattern rather than flattening it, unlike some synthetic alternatives.
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